Heart Center Leipzig, Department of Cardiology, University Leipzig
Head of Research Laboratory
2013 - 2017
Heart Center Leipzig, Dept. Electrophysiology, University Leipzig
PostDoc with focus on atrial fibrillation genetics,
pathomechanisms and biomarkers
2012 - 2013
Heart Center Dresden, Technical University Dresden
PostDoc with focus on pathophysiology of heart valve disease
2011 - 2012
InstaG GmbH Leipzig (postgraduate education for scientific staff)
2007 - 2010
University Hospital for Children and Adolescents, University Leipzig
Postdoctoral scientist with focus on adipocyte-biology
2003 - 2007
Institute for Vascular Medicine, University Jena
PhD student with focus on gene expression profiling in sports medicine
Education
2019
Habilitation in experimental cardiology, University Leipzig
thesis "Genetic Background and Biomarkers of Atrial Fibrillation Progression and Recurrence"
2003 - 2007
Graduation in molecular cell biology
thesis "Analysis of alterations in gene expression profiles of white blood cells in human in response to physical
exercise", Friedrich-Schiller University, Jena
1998 - 2003
student in biological sciences at Friedrich-Schiller University, Jena
diploma thesis - "Siderophores of the pathogen of soy bean Pseudomonas syringae pv. glycinea and it's bacterial antagonists
Pseudomonas syringae pv. syringae and Pantoea agglomerans"
Scientific interest
OMICs, in silico biology, biomarkers, cardiovascular pathomechanisms, cell biology
Publications (10 most important during last five years)
Arginine derivatives in atrial fibrillation progression phenotypes. Büttner P, Bahls M, Böger RH, Hindricks G,
Thiele H, Schwedhelm E, Kornej J. J Mol Med (Berl). 2020 Jul;98(7):999-1008.
doi: 10.1007/s00109-020-01932-9. Epub 2020 Jun 6
IF 4.43
Selenoprotein P in Myocardial Infarction With Cardiogenic Shock. Büttner P, Obradovic D, Wunderlich S, Feistritzer HJ,
Holzwirth E, Lauten P, Fuernau G, de Waha-Thiele S, Desch S, Thiele H. Shock. 2020 Jan;53(1):58-62.
doi: 10.1097/SHK.0000000000001342
IF 2.96
Myeloperoxidase in atrial fibrillation: association with progression, origin and influence of renin-angiotensin system antagonists.
Holzwirth E, Kornej J, Erbs S, Obradovic D, Bollmann A, Hindricks G, Thiele H, Büttner P. Clin Res Cardiol.
2020 Mar;109(3):324-330.
doi: 10.1007/s00392-019-01512-z. Epub 2019 Jun 24
IF 5.27
Atrial Fibrillation Is Associated With Alterations in HDL Function, Metabolism, and Particle Number. Markus Trieb, Jelena Kornej,
Eva Knuplez, Gerhard Hindricks, Holger Thiele, Philipp Sommer, Hubert Scharnagl, Nikolaos Dagres, Borislav Dinov, Andreas Bollmann,
Daniela Husser, Gunther Marsche, Petra Büttner. Basic Res Cardiol 2019 May 8;114(4):27.
doi: 10.1007/s00395-019-0735-0
IF 11.98
EGF (Epidermal Growth Factor) Receptor Ligands in Atrial Fibrillation: From Genomic Evidence to the Identification of New Players.
Büttner P, Werner S, Sommer P, Burkhardt R, Zeynalova S, Baber R, Bollmann A, Husser-Bollmann D, Thiery J, Hindricks G,
Thiele H, Kornej J. Circ Arrhythm Electrophysiol. 2019 Apr;12(4):e007212.
doi: 10.1161/CIRCEP.119.007212
IF 4.39
Circulating proteomic patterns in AF related left atrial remodeling indicate involvement of coagulation and complement cascade. Kornej J,
Büttner P, Hammer E, Engelmann B, Dinov B, Sommer P, Husser D, Hindricks G, Völker U, Bollmann A. PLoS One. 2018
Nov 29;13(11):e0198461.
Role of NT-proANP and NT-proBNP in patients with atrial fibrillation: Association with atrial fibrillation progression phenotypes.
Büttner P, Schumacher K, Dinov B, Zeynalova S, Sommer P, Bollmann A, Husser D, Hindricks G, Kornej J. Heart Rhythm.
2018 Aug;15(8):1132-1137.
doi: 10.1016/j.hrthm.2018.03.021
IF 4.44
Label-free Imaging of Myocardial Remodeling in Atrial Fibrillation Using Nonlinear Optical Microscopy: A Feasibility Study.
Büttner P, Galli R, Husser D, Bollmann A. J Atr Fibrillation. 2018 Feb 28;10(5):1644.
doi: 10.4022/jafib.1644. eCollection 2018 Feb.
Association of atrial fibrillation susceptibility genes, atrial fibrillation phenotypes and response to catheter ablation: a gene-based
analysis of GWAS data. Husser D, Büttner P, Ueberham L, Dinov B, Sommer P, Arya A, Hindricks G, Bollmann A. J Transl Med.
2017 Apr 5;15(1):71.
doi: 10.1186/s12967-017-1170-3
IF 4.12
Genomic contributors to atrial electroanatomical remodeling and atrial fibrillation progression: Pathway enrichment analysis of GWAS data.
Husser D, Ueberham L, Dinov B, Kosiuk J, Kornej J, Hindricks G, Shoemaker MB, Roden DM, Bollmann A, Büttner P. Sci Rep.
2016 Nov 18;6:36630.
doi: 10.1038/srep36630
IF 4.26
Awards
"Poster of the day award" at the International Swiss MedLab and 8th Alps Adria congress 2004 Lucerne
